Detalhe da pesquisa
1.
Novel Paracrine Action of Endothelium Enhances Glucose Uptake in Muscle and Fat.
Circ Res
; 129(7): 720-734, 2021 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34420367
2.
PTPRD and DCC Are Novel BACE1 Substrates Differentially Expressed in Alzheimer's Disease: A Data Mining and Bioinformatics Study.
Int J Mol Sci
; 23(9)2022 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35562959
3.
Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications.
Blood
; 133(11): 1233-1244, 2019 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30545831
4.
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage.
Am J Physiol Cell Physiol
; 319(1): C64-C74, 2020 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32401607
5.
Extending enzyme molecular recognition with an expanded amino acid alphabet.
Proc Natl Acad Sci U S A
; 114(10): 2610-2615, 2017 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28196894
6.
Molecular mechanism of ligand recognition by membrane transport protein, Mhp1.
EMBO J
; 33(16): 1831-44, 2014 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24952894
7.
A virtual high-throughput screening approach to the discovery of novel inhibitors of the bacterial leucine transporter, LeuT.
Mol Membr Biol
; 30(2): 184-94, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22908980
8.
The ß-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/ß-Catenin/Notch Signaling Axis.
J Invest Dermatol
; 2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38570030
9.
Recent developments in the structural characterisation of the IR and IGF1R: implications for the design of IR-IGF1R hybrid receptor modulators.
RSC Med Chem
; 13(4): 360-374, 2022 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35647546
10.
Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity.
Adipocyte
; 11(1): 366-378, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35734881
11.
Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells.
Sci Rep
; 11(1): 4054, 2021 02 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33603063
12.
The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors.
Mol Microbiol
; 72(2): 335-43, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19298367
13.
Benzothioxalone derivatives as novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferases (MurA and MurZ).
J Antimicrob Chemother
; 65(12): 2566-73, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20861142
14.
Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site.
Commun Biol
; 3(1): 704, 2020 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33230284
15.
Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine.
Nat Commun
; 8(1): 1939, 2017 12 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29208891
16.
Computational methods to identify new antibacterial targets.
Chem Biol Drug Des
; 85(1): 22-9, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24974974
17.
Identification of selective inhibitors of the potassium channel Kv1.1-1.2((3)) by high-throughput virtual screening and automated patch clamp.
ChemMedChem
; 7(10): 1775-83, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22473914
18.
Structure guided development of potent reversibly binding penicillin binding protein inhibitors.
ACS Med Chem Lett
; 2(3): 219-23, 2011 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24900305
19.
Structure-based discovery of antibacterial drugs.
Nat Rev Microbiol
; 8(7): 501-10, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20551974